For research use only · Not for human use
Epithalon
Tetrapeptide from telomere and aging research
In short
Epithalon is a synthetic 4-amino-acid peptide modeled on a pineal gland extract (epithalamin). It is known from telomerase and aging-biology research.
Evidence level: Mostly preclinicalMost publications come from a single research group and are mostly animal/cell studies.
Size
- Independently tested. Janoshik Analytical results published.
- QR verification. An authenticity code on every box.
Chemistry
| CAS# | Formula | Molar mass |
|---|---|---|
| 307297-39-8 | C14H22N4O9 | 390.35 g/mol |
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Request certificateWhat is Epithalon?
Epithalon is a synthetic tetrapeptide with the sequence Ala-Glu-Asp-Gly, originally derived from epithalamin, a pineal gland extract. It has been examined in preclinical and in vitro research investigating telomerase enzyme activity, chromosomal telomere dynamics, and gene-expression patterns in cultured cell lines.
Epithalon was developed in the former Soviet Union during the 1980s by Professor Vladimir Khavinson, whose laboratory was investigating the biochemistry of the pineal gland. Khavinson's group was characterizing how pineal-derived peptide fractions changed across different research models.
From pineal gland extracts, Khavinson's team isolated a peptide fraction named epithalamin. To produce a defined, reproducible research compound, the group synthesized a simpler four-amino-acid sequence (Ala-Glu-Asp-Gly) and designated it Epithalon.
The peptide has since been examined in preclinical and in vitro publications exploring telomerase enzyme activity and chromosomal telomere measurements. This product is intended for research use only.
How should Epithalon be stored?
Research peptides are supplied lyophilized (freeze-dried) . Keep sealed vials cool, dry, and protected from light until reconstitution.
After reconstitution, refrigerate prepared solutions and use sterile technique. For general laboratory diluent and handling notes, see lyophilized peptide reconstitution .
Related research compounds
References
- Khavinson VKh, et al. Epitalon peptide induces telomerase activity and telomere elongation in human somatic cells. Bulletin of Experimental Biology and Medicine. 2003.
- Khavinson VKh, et al. Effect of epithalon on the lifespan increase in Drosophila melanogaster. Mechanisms of Ageing and Development. 2000.
Epithalon is available for laboratory research purposes only.