Thymosin Alpha-1

Thymosin Alpha-1 (Tα1) is a synthetic 28-amino-acid, N-terminally acetylated peptide (Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN) derived from the precursor protein prothymosin alpha and widely used as a reference immunomodulatory peptide in laboratory research. It is supplied as a lyophilized powder strictly for research use only and is not for human consumption.

Thymosin Alpha-1 (Tα1) was first isolated in the 1970s from thymosin fraction 5, a thymic tissue extract characterized by Allan Goldstein and colleagues. It was later identified as a 28-amino-acid, N-terminally acetylated fragment of the precursor protein prothymosin alpha, and is commonly described as a reference immunomodulatory thymic peptide.

As a research compound, Thymosin Alpha-1 has been the subject of an extensive preclinical and in vitro literature examining immune-signaling mechanisms — including T-cell maturation, Toll-like-receptor and dendritic-cell signaling, natural-killer-cell activity, and cytokine networks.

Research peptides are supplied lyophilized (freeze-dried) . Keep sealed vials cool, dry, and protected from light until reconstitution.

After reconstitution, refrigerate prepared solutions and use sterile technique. For general laboratory diluent and handling notes, see lyophilized peptide reconstitution .