Melanotan II

Melanotan 2 (MT-2) is a synthetic cyclic analog of α-MSH that has been examined in preclinical and in vitro research for its interactions with melanocortin receptor subtypes (MC1R, MC3R, MC4R, MC5R).

Melanotan 2 originated from melanocortin research at the University of Arizona in the 1980s. Scientists there were investigating synthetic analogs of α-MSH to characterize melanocortin receptor binding affinity in cell-culture models.

An earlier compound, Melanotan 1, had a short half-life in laboratory assays. Researchers modified its structure to create Melanotan 2—a cyclic heptapeptide analog. Subsequent investigations characterized its interactions across multiple melanocortin receptor subtypes.

Since then, Melanotan 2 has appeared in peer-reviewed preclinical publications examining melanocortin receptor pharmacology in cell culture and rodent models. This product is intended for research use only.

Research peptides are supplied lyophilized (freeze-dried) . Keep sealed vials cool, dry, and protected from light until reconstitution.

After reconstitution, refrigerate prepared solutions and use sterile technique. For general laboratory diluent and handling notes, see lyophilized peptide reconstitution .