Glutathione

Glutathione (GSH) is a naturally occurring reduced tripeptide (γ-glutamyl-cysteinyl-glycine) present in most mammalian cells. It has been examined in preclinical research for its participation in intracellular thiol redox chemistry, glutathione S-transferase conjugation reactions, and GSH/GSSG-dependent signaling.

Glutathione was first identified in 1888 by French researcher J. de Rey-Pailhade, who isolated the compound from yeast and called it 'philothion.' The name was later changed to glutathione in 1921 when Frederick Hopkins crystallized it and characterized its structure as a tripeptide containing a sulfhydryl group.

Research on glutathione expanded through the mid-20th century as biochemists characterized its distribution across mammalian cell types. Studies documented glutathione synthesis in nearly every cell type, with particularly high concentrations observed in hepatic tissue.

Glutathione has appeared in peer-reviewed publications spanning biochemistry, toxicology, immunology, and cell biology, where it is referenced in research on intracellular redox chemistry and thiol-dependent enzymatic pathways. This product is intended for research use only.

Research peptides are supplied lyophilized (freeze-dried) . Keep sealed vials cool, dry, and protected from light until reconstitution.

After reconstitution, refrigerate prepared solutions and use sterile technique. For general laboratory diluent and handling notes, see lyophilized peptide reconstitution .